- Category Advanced Certificate Program
Explore the immune system’s potential to fight cancer!
In today’s modern world, the science of therapeutic intervention has progressed a long way. With the emergence of many chronic conditions like cancer and autoimmune conditions, understanding the genetic basis for immune response has begun to gain greater attention. The adaptive nature of the human immune system is one of the major sources of greater variation in human genes, with some of the sites of variation being single nucleotide polymorphisms, the HLA locus, the chromosomal region that helps to distinguish self from non-self, uniquely randomized T- and B-cell receptor genes that encode our immune repertoires and so on. This has thus resulted in an understanding that gives importance to genetic factors in immune interventions.
Immunogenomics, an information science, combines the fields of immunology and genomics in developing enhanced immune responses for conditions like cancer. At present, this science has developed based on the existing sequencing techniques, along with microarrays, mass spectrometry, NMR, chromatography, PCR, mass cytometry, data repositories, experimental designs, and statistical methods. It is extensively being used for developing personalised medications for the treatment of conditions like cancer. However, this is restricted to cancer while importance is not being sufficiently given to other conditions that can be better treated and managed using personalised medications and interventions. There are also exists some gaps in our due to limitations in methodologies available such as mapping interactions amongst the microbiome and the host immune system.
This field has immense potential in providing insights into understanding the changes to the human immune system with the progression of illnesses. Other potential areas of medical relevance include immune regeneration, immunosenescence, immune decline, and heterochthonous immunity.
The field of Immunogenomics further builds on the foundations of Cancer Biology. The course provides an in-depth overview of the genomics of immune cells and tumour cells that are used to build immune response against cancer. The Immunogenomics course will allow you understand the molecular changes in our immune system and the biological mechanisms underlying the development of cancers. Based on these concepts, the course is designed to help develop finer understanding of treatment and health.